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Animal Studies in LFMI
Work in LFMI often makes use of animal models,
especially rodents. This work is done in a manner that is consistent with all of the rules and regulations
of the NINDS IACUC. Rodents are used for three types of studies:
- Advancing non-invasive assessment of brain function using anatomical, functional, and molecular imaging techniques
- Elucidating the regulation and control of cellular energy metabolism and the role of creatine kinase
- Development of imaging techniques useful for analyzing transgenic mice to help with functional genomic studies
- Understanding control of cerbral microcirculation
- Establishing the marmoset as an animal modal for marmost study of the brain
Active LFMI animal protocols:
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ASP 1142-09 | Imaging Brain Function in Rats and Mice | | | |
ASP 1160-10 | Imaging Brain Plasticity in Rats and Mice | | | |
ASP 1321-10 | Manganese Based Radiotracers for PET Imaging in Rodents | | | |
03-N-0142 | Development of 7 Tesla MRI Methodology for Anatomical Functional and Spectroscopic Imaging of the Brain | | | |
05-N-0179 | MRI Measurement of Brain Metabolism Across the Sleep-Wake Cycle | | | |
ASP 1291-08 | Functional MRI in Awake Rodents | | | |
ASP 1199-11 | Breeding of Mice for Experiments in the LFMI | | |
How to get started?
Work with animals in LFMI is done under
the supervision of the NINDS IACUC and the NIH NMR Center Mouse Imaging Committee. For a detailed
description of procedures that are followed prior to starting any animal studies in LFMI, please go to the
NMRF web site.
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